Protocol · NP · Mississippi

Practice Protocol for Nurse Practitioners in Mississippi

Required. Mississippi law names the instrument a Board-Approved Protocol or Standing Order. Below: the board that governs it, what it must contain, and the terms it has to carry.

Practice authoritySupervision required
Written agreementAgreement required
What Mississippi calls itBoard-Approved Protocol or Standing Order
Governing boardMississippi Board of Nursing and the Mississippi Board of Pharmacy
Agreement familySupervising Physician
Research date2026-09-03 · clauses 2026-09-03

No independent-practice pathway exists in current law (§ 73-15-20) — a collaborative relationship plus Board-approved protocol is required permanently, not conditioned on any hours/years threshold. A one-time 1,000-2,000-hour 'monitored practice' onboarding period (see prescriptive authority notes) does not end the collaborative requirement.

What a Mississippi Board-Approved Protocol or Standing Order must contain

Governed by the Mississippi Board of Nursing and the Mississippi Board of Pharmacy. Each numbered item is a statutory requirement the Board-Approved Protocol or Standing Order must satisfy.

  1. The Nurse Practitioner shall maintain a collaborative and consultative relationship with the Physician, as required by Miss. Code Ann. § 73-15-20, and shall practice under a Board-approved protocol or standing order. The Physician shall hold an unrestricted Mississippi medical license and unrestricted prescriptive authority.

    Source: Miss. Code Ann. § 73-15-20

  2. The Physician shall review a random sample of at least ten percent (10%), or twenty (20) charts, whichever is less, of the Nurse Practitioner's patients each month, and the Physician and the Nurse Practitioner shall hold documented, face-to-face quality assurance meetings at least quarterly. Patients may be treated at a location up to seventy-five (75) miles from the Physician's primary office without additional Board of Medical Licensure appearance; a site beyond that distance is a "free-standing clinic" requiring the Physician to appear before the Board of Medical Licensure, in person or by telephone, before collaborating with the Nurse Practitioner there.

    Source: Miss. Admin. Code Title 30, Part 2630, Ch. 1, Rule 1.2-1.3

  3. The Board-Approved Protocol or Standing Order also carries 1 scope, 1 education and 1 registration clauses, authored in the document itself.

Statutes and rules these clauses cite

  1. Miss. Code Ann. § 73-15-20statute

    Advanced practice registered nurse collaborative/consultative relationship and Board-approved protocol requirement, as compiled in the Board of Nursing's official Nurse Practice Act.

  2. Miss. Admin. Code Title 30, Part 2630, Ch. 1, Rule 1.2-1.3board rule

    Mississippi State Board of Medical Licensure rules governing physician collaboration with nurse practitioners: chart review, quarterly QA meetings, and the 75-mile free-standing-clinic rule.

Terms it has to carry

Ratio, proximity, chart review, meeting and prescribing terms the Board-Approved Protocol or Standing Order has to carry, from Mississippi's supervision rules.

Proximity

Available remotely (no on-site requirement)

No mileage/radius requirement is codified for NPs (unlike PA's 30-mile rule) — statute/rule require only that the APRN 'be able to communicate reliably' with the collaborating physician (§ 73-15-20(7)(b); Admin. Code Part 2840, Rule 1.4C).

Supervision ratio

Not codified — no cap on file

Chart review

Not codified — left to the agreement

Meeting cadence

Not codified — left to the agreement

Prescriptive authority

Covered by the practice agreement · controlled substances permitted

Before practicing at a site without a qualifying provider physically on premises, a new APRN must complete 2,000 monitored practice hours (if <1 year RN experience pre-APRN) or 1,000 hours (if ≥1 year) with a qualifying provider on-site (Part 2840, Rule 1.3) — a one-time site-specific onboarding step, not a pathway to eventual independence; the collaborative agreement itself never ends.

Written agreement

Required

Practice ownership (corporate practice of medicine)

Licensee-only ownership required — Same as the `pa` entry — Miss. Code Ann. § 79-10-31 restricts PC shareholders in medical-service corporations to licensed physicians; no NP co-ownership of medical PCs/PLLCs.

Sources for the supervision rules (2)
  • Miss. Code Ann. § 73-15-20 — Advanced Practice Registered Nurses
  • Mississippi Admin. Code Title 30, Part 2840, Ch. 1 — APRN practice
How the relationship works day to day
Who has to be where, how often you meet, and what the physician costs: Nurse Practitioner in Mississippi on collaborativeagreement.com.

About Mississippi's rules

Mississippi has no independent-practice pathway for NPs/APRNs — a collaborative relationship plus Board-approved written protocol is required for the life of the license. Multiple 2025-2026 NP full-practice-authority bills (H.B. 813, H.B. 98, S.B. 2178) remain unconfirmed as enacted — re-verify § 73-15-20 each session.

Other clinicians in Mississippi: see the state overview.