Protocol · PharmD · South Dakota

Practice Protocol for Pharmacists in South Dakota

Required. South Dakota law names the instrument a Protocol. Below: the board that governs it, what it must contain, and the terms it has to carry.

Practice authoritySupervision required
Written agreementAgreement required
What South Dakota calls itProtocol
Governing boardSouth Dakota Board of Pharmacy
Agreement familyDelegation of Services
Research date2026-09-03 · clauses 2026-09-03

Represents SD's protocol-based drug-therapy-management authority (SDCL 36-11-19.1(6)), not ordinary dispensing licensure, which is out of scope here. Pharmacists may 'initiate or modify drug therapy by protocol...established and approved within a licensed health care facility or by a practitioner authorized to prescribe drugs' — recently amended by SL 2025, ch 154.

What a South Dakota Protocol must contain

Governed by the South Dakota Board of Pharmacy. Each numbered item is a statutory requirement the Protocol must satisfy.

  1. South Dakota does not require the Pharmacist to enter into a formal collaborative practice agreement with a physician as a condition of pharmacy licensure or practice. Rather, S.D. Codified Laws § 36-11-19.1 permits the Pharmacist to initiate or modify a patient's drug therapy pursuant to a protocol established and approved either within a licensed health care facility or by a practitioner authorized to prescribe drugs; South Dakota statute does not itself prescribe mandatory contents, a board-filing requirement, or a renewal cycle for that protocol.

    Source: S.D. Codified Laws § 36-11-19.1

  2. This Agreement's terms regarding the Pharmacist accordingly serve to define the working relationship between the Parties and any protocol they elect to establish under S.D. Codified Laws § 36-11-19.1, and are not themselves required by South Dakota law as a condition of the Pharmacist's authority to practice.

  3. The Protocol also carries 1 scope, 1 education and 1 registration clauses, authored in the document itself.

Statutes and rules these clauses cite

  1. S.D. Codified Laws § 36-11-19.1statute

    Authority of registered pharmacists to initiate or modify drug therapy pursuant to a facility- or practitioner-established protocol; South Dakota does not define or require a formal collaborative practice agreement for pharmacists in this chapter.

Terms it has to carry

Ratio, proximity, chart review, meeting and prescribing terms the Protocol has to carry, from South Dakota's supervision rules.

Proximity

Not codified — left to the agreement

Supervision ratio

Not codified — no cap on file

Chart review

Not codified — left to the agreement

Meeting cadence

Not codified — left to the agreement

Prescriptive authority

Covered by the practice agreement · no controlled-substance authority

SDCL 36-11-2.2 expressly states the practice of pharmacy 'does not authorize a pharmacist to prescribe drugs as a practitioner.' The protocol-based drug-therapy-management authority in 36-11-19.1(6) allows initiating/modifying already-prescribed therapy, not independent prescribing; no controlled-substance-specific authority was found.

Written agreement

Required

South Dakota's statute uses 'protocol ... established and approved' rather than a named 'collaborative practice agreement' document, a functionally similar gating concept to other states' CPAs; the exact form and content requirements are not spelled out.

Practice ownership (corporate practice of medicine)

Non-licensee ownership permitted — No pharmacist-ownership requirement identified for a general pharmacy permit, consistent with the permissive pattern in most states

Sources for the supervision rules (2)
How the relationship works day to day
Who has to be where, how often you meet, and what the physician costs: Pharmacist in South Dakota on collaborativeagreement.com.

About South Dakota's rules

SD is unusually permissive: NP/CNM need only 1,040 practice hours (or a collaborative agreement with ANY physician OR already-independent NP/CNM) to become fully independent (SDCL 36-9A), and a 2025 reform (SL 2025, ch 149) gives PAs the same kind of pathway after 6,000 hours plus NCCPA certification. Older sources citing a fixed PA-per-physician ratio are now outdated — that cap was repealed.

Other clinicians in South Dakota: see the state overview.